We are now offering invites to attend our workshop. From our partner ChemStream Geert Deroover will present on some interesting results on modifying the surfaces of particles and pigments. REGISTER here to hear about the value of this technology ChemStream is an innovative chemical contract research company, developing customized sustainable materials and sustainable technology with…
The ROBOX Project
Oxygen functionalities are key functional groups in many of today’s chemicals and materials. The efficient introductions of oxygen-functionalities into raw materials are key chemical transformations in bulk and fine chemicals. Innovative bio-catalytic oxidation routes using molecular oxygen (from air) under benign and mild (pH) conditions such as ambient temperature and pressure can greatly improve the sustainability and economics of processes, but are so far mainly been applied in the pharma segments. In this segment, the enzyme-catalyzed step often represents the highest added value and the high price of the end-product (> €1000/kg) justifies less than optimal enzyme production and limitations in its catalytic efficiency. In order to achieve the widening of industrial application of enzymatic bio-oxidation processes to also larger volume but lower price chemical markets, ROBOX will demonstrate the techno-economic viability of bio-transformations of four types of robust oxidative enzymes: P450 monooxygenases (P450s), Baeyer-Villiger MonoOxygenase (BVMOs), Alcohol DeHydrogenase (ADH) and Alcohol OXidase (AOX) for which target reactions have already been validated on lab-scale in pharma, nutrition, fine & specialty chemicals and materials applications.
The introduction of ROBOX bio-oxidation processes is expected to bring substantial reductions in cost (up to -50%), energy use (-60%), chemicals (-16%) and GHG-emissions (-50%).
The ROBOX project has an integrated work-flow structure of 7 work packages.
The intensive networking with our scientific partners enables us to keep at the front line of top-level research and strengthens the knowledge base in the field of industrial biotechnology.
ROBOX has one target for the use of Bayer-Villiger Monooxygenases to produce caprolactone. Recently a publication reports a detailed study on an alternative route from glucose. “Sustainable production of chemical intermediates for nylon manufacture: A techno-economic analysis for renewable production of caprolactone” If you want to find out more about recent demonstrations of enzyme catalysis…
The joint ROBOX/CARBAZYMES final meeting to disseminate and promote these two H2020 projects aimed at making enzymes more readily available to industry will take place at Dechema Frankfurt on 14th Feb 2019. If you want to know more contact us. If you have an interest in Industrial Biocatalysis and wish to attend to attend —…