ROBOX at “Day of Chemistry”

On Saturday 6th of October ROBOX presented at the Day of Chemistry at Chemelot in Geleen (NL) and Maastricht University presented to an open general audience. In total there were 2500 visitors and the ROBOX attracted interest in the area of biotechnology. poster Dr Katrien Bernaerts presents ROBOX to a wider audience. Chemelot stands for…

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ROBOX at CPhI

Recently ROBOX oxidation technology was recently widely publicized at the leading pharmaceutical industrial showcase exhibition CPhI in Madrid. Led by our partner TUG this was an excellent opportunity to promote our use of CYP450 technology to produce pharmaceutically relevant metabolites. CLE also promoted their combination of ADH and NOX technology for alcohol oxidation. IF YOU…

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Experimental Protocols for Generating Focused Mutant Libraries and Screening for Thermostable Proteins

Our partner RUG have published a detailed protocol to generate mutant libraries experimentally by primer design, mutagenesis, protein production and screening and then mutation combination strategies that can yield stabilized mutants with increases in apparent melting temperature of 20–35°C and vastly increased half-lives with resistance to cosolvents. These mutants were designed using algorithms to predict…

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ROBOX Workshop and Final Meeting

The ROBOX project is planning a final meeting and workshop on Feb 13th and 14th 2019 to promote all the results and look for ways other stakeholders can get involved with use and exploitation. The major results from all our demonstation projects will be released. Please get in touch if you are interested in biooxidations.…

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