ChemBiOx 2019 – a student led conference

This two days of cutting-edge research on July 30th & 31st in the idyllic setting of one of Oxford’s most historic colleges – Worcester College. ChemBiOx 2019 is a student-led chemical biology and medicinal chemistry conference organised by the inaugural cohort of the University of Oxford’s doctoral training partnership with GSK and the Francis Crick…

Self-sufficient fused redox redox enzymes (Baeyer-Villiger monooxygenases/alcohol dehydrogenases)s

Read the latest ROBOX paper from our partner RUG – “What to sacrifice? Fusions of cofactor regenerating enzymes with Baeyer-Villiger monooxygenases and alcohol dehydrogenases for self-sufficient redox biocatalysis” This is the latest of our publications that demonstrate the usefulness of our enzymes in factsheets and these reactions have been used to synthesize multi-kilogram quantities of…

Vanilla and other flavors.

As you may have seen the ROBOX project has been developing a method to produce Vanillin. Our results have been sent for publication as a paper “Enzymatic synthesis of vanillin catalyzed by an eugenol oxidase” which will be available soon. These results have also been highlighted in our detailed factsheets and the scaled up reaction…

An Enzyme Cascade Synthesis of Vanillin

ROBOX has been developing scaleable routes to improved routes to vanillin (see our publications) This report by University of Stuttgart demonstrates the great interest in using oxidative enzymes to produce vanillin. Vanillin is one of the most widely used flavouring compounds worldwide as a flavour ingredient for food and beverages as well as a fragrance…

ROBOX helps create Biotech jobs.

Our ROBOX partner Givaudan who are committed to growing their efforts in the areas of biotechnology and biocatalysis especially after the success of the ROBOX project are currently searching for a (Senior) Research Scientist (PhD), specialized in fermentation, and a Senior Research Technician (also suitable for BSc or MSc), specialized in fermentation and/or biocatalysis: To…

Detailed Factsheets for ROBOX Reactions and Enzymes

To find out more about ROBOX enzymes and reactions read these detailed one page descriptions of enzyme characterizations or reaction parameters. ROBOX Technology Information 1. P450 Aromatic Hydroxylations 2. P450 API Metabolites on Larger Scale 3. P450 Hydroxylation of Alkenes 4. BVMO oxidation of trimethyl-cyclohexanone 5. BVMO oxidation of cyclopentadecanone 6. AOX vanillin synthesis from…