Ancestral Sequence Reconstruction leads to Robust Enzymes
Ancestral Sequence Reconstruction leads to Robust Enzymes ROBOX has been highly focussed on developing commercial biocatalysts that requires robust enzymes that can withstand elevated temperatures and long incubations as well as stability to organic substrates and solvents. In an interesting approach to this problem Elizabeth Gillam and coworkers have used ancestral reconstruction of pre-Cambrian enzymes…