Our latest publication describes further developments at our partner RUG in fusion enzymes for co-factor recycling.
See “What to sacrifice? Fusions of cofactor regenerating enzymes with Baeyer-Villiger monooxygenases and alcohol dehydrogenases for self-sufficient redox biocatalysis”
Read more about our portfolio of cytochrome P450 enzymes in Exploring the Biocatalytic Potential of a Self‐Sufficient Cytochrome P450 from Thermothelomyces thermophila
Read our latest review article on monooxygenases
Beyond active site residues: overall structural dynamics control catalysis in flavin-containing and heme-containing monooxygenases
Read our publication “A hydroquinone-specific screening system for directed P450 evolution” This was published by our partner RWTH Aachen and describes the direct hydroxylation of benzene to hydroquinone (HQ) under mild reaction conditions that is a challenging task for chemical catalysts.
High performing immobilized Baeyer-Villiger monooxygenase and glucose dehydrogenase for the synthesis of ε-caprolactone derivative
This paper describes co-immobilized biocatalyst enzymes that allows cofactor regeneration and higher yields.
See our latest paper that demonstrates the environmental metrics of our biocatalysis technology
A prospective life‐cycle assessment (LCA) of monomer synthesis: Comparison of biocatalytic and oxidative chemistry
See our VIP award winning publication on fused oxidation enzymes
“Design of Artificial Alcohol Oxidases: Alcohol Dehydrogenase–NADPH Oxidase Fusions for Continuous Oxidations”
Our latest publication from RUG/UP has applied cumulative alanine mutagenesis approach to cyclohexanone monooxygenase from Thermocrispum municipale, a flavin-dependent Baeyer-Villiger monooxygenase to demonstrate “Side-Chain Pruning Has Limited Impact on Substrate Preference in a Promiscuous Enzyme”
Our partner RUG have published a paper on how ROBOX catalysts can be used to add value to glycerol – a byproduct of biodiesel production that is treated as waste.
“Structure-based engineering of Phanerochaete chrysosporium alcohol oxidase for enhanced oxidative power towards glycerol”
See ROBOX latest publication from RUG