Here you find the latest news about this project ‘H2020robox’.
ROBOX were recently part of the Innovative Radar Initiative (see video of how the EU H2020 program supports many established and new ideas that help EU citizens) Our partner TUG Graz were finalists in the “Industrial & Enabling Tech” prize category InnoSyn were finalists in the “Best Young SME” category. The Innovation Radar is a…
Physicists pinpoint a simple mechanism that makes bacteria resistant to antibiotics
In this report the importantance of multidisciplinary science is used in demonstrating the value of materials research and physics in medicine.
This discovery which provides new insights into how germs adapt and behave at a level of detail never seen before!
In this detailed presentation from our workshop in Dechema, Frankfurt Martin Schürmann from InnoSyn describes our results for larger scale biooxidations and how they were made safe using air/oxygen as a clean oxidant with no toxic metals. These studies are supported by detailed Techno-Economic metrics using methods and calculations with experts from our experts from…
In this latest video John Whittall from our ROBOX partner UNIMAN describes our work in the area of pharmaceutical metabolites and how our WP6 has been implemented
Our partner cLEcta have had their patent “KETOREDUCTASES” WO 2019/012095 A1 published. This invention relates to ketoreductases and their use that are particularly useful for enzymatically catalyzing the reduction of ketones to chiral or non-chiral secondary alcohols and oxidation of chiral or non-chiral secondary alcohols to ketones. Andreas Vogel (one of the inventors) from cLEcta…
In our publication “A Prospective Life Cycle Assessment (LCA) of Monomer Synthesis: Comparison of Biocatalytic and Oxidative Chemistry” out partners University of Maastrict and DTU have analysed our biochemical synthesis of lactones obtained by Baeyer–Villiger oxidation and compared this to more traditional chemical methods. This allowed us to quantify the environmental impact of our products…
Geert Deroover from Chemstream delivers his presentation In this novel development our partner Chemstream have developed a range of techniques to produce improved formulations for inks based on biooxidative enzyme modifications of pigments and polymers. This presentation given at our recent workshop at Dechema describes some of the developments in “ROBOX pigment oxidation by ChemStream”…
1. What can oxidative biocatalysis do for polymeric materials? Our partners from Maastricht describe the use of Bayer-Villiger monooxygenases to synthesize substitituted caprolactones which are used to make novel polymers. 2. Selective alcohol oxidations with artificial oxidases: alcohol dehydrogenase – NADPH oxidase fusions RUG Groningen describe resolution of alcohols by enantiomeric oxidation with these fusion…
Read our publication on this topic. It describes the direct hydroxylation of benzene to hydroquinone (HQ) under mild reaction conditions is a challenging task for chemical catalysts. A screening protocol designed for screening of P450 variants capable of producing hydroquinones. The hydroquinone quantification assay is based on the interaction of 4-nitrophenylacetonitrile (NpCN) with hydroquinones under…
Listen to Marc Biermann from the leading fragrance house, Givauden. He describes the development of tools to synthesize improved fragrance ingredients using ROBOX biotechnology.