The joint ROBOX/CARBAZYMES final meeting to disseminate and promote these two H2020 projects aimed at making enzymes more readily available to industry will take place at Dechema Frankfurt on 14th Feb 2019. If you want to know more contact us. If you have an interest in Industrial Biocatalysis and wish to attend to attend —…
Leading researchers at many European plant and life sciences research centres and institutes haurgently calls upon European policy makers to safeguard gene-editing technologies in plant science and agriculture. Plant breeding started about 10,000 years ago by selecton of the best seeds from crops obtained through spontaneous genetic mutations and then using crossbreeding to produce new…
Ancestral Sequence Reconstruction leads to Robust Enzymes ROBOX has been highly focussed on developing commercial biocatalysts that requires robust enzymes that can withstand elevated temperatures and long incubations as well as stability to organic substrates and solvents. In an interesting approach to this problem Elizabeth Gillam and coworkers have used ancestral reconstruction of pre-Cambrian enzymes…
Here are our latest posters that give more details about our results. Please contact us if you wish to find out more. From ACIB some results on drug metabolite synthesis – Combinatorial Optimization strategies to increase Human P450 catalytic Activity in whole cell Biotransformations From DTU two posters on implementation of biooxidation – Kinetic Evaluation…
At the recent trade fair our partner c-LEcta released details of the alcohol oxidation methods developed in the ROBOX project.
For more details see their poster –
Robust industrial alcohol oxidation and cofactor regeneration using optimized ADH and NOX
Two ROBOX participants have been nominated for the EU’s Innovation Radar prizes. InnoSyn is in the category as one of the 9 “Best Young SME 2018” and our partner TUG have been nominated for “Industrial & Enabling Tech 2018” in this competition for organisations participating in Horizon2020 projects. We would like to encourage as many…
EU Parliament votes to reduce plastic use. Single-use plastic items such as plates, cutlery, straws, balloon sticks or cotton buds, will be banned in the EU under new plans and these products which make up over 70% of marine plastic litter. – single-use cutlery, cotton buds, straws and stirrers to be banned from 2021 –…
Cytochrome P450 enzymes are one of the main targets for ROBOX and have now been reported to have applications to make biorenewable chemicals from lignin – a major byproduct of the timber and paper industries. A new class of CYP450s – the family N were discovered. These can convert guaiacol into catechol (and also the…
One of the problems facing potential users wishing to replicate enzyme technology is the availability of the enzyes – our partner RUG now make some ROBOX robust enzymes available: –Eugenol oxidase (EUGO) Robust oxidase acting on phenolic compounds details in Nguyen et al. (2016) Chembiochem. 17:1359-1366 –Thermostable cyclohexanone monooxygenase (TmCHMO) Robust Baeyer-Villiger monooxygenase acting on…
The 6th international Novel Enzymes conference Darmstadt has recently completed with four speakers presenting results from from ROBOX
Martin Schurman from INNOSYN presents about practical applications of ROBOX technology
ROBOX also supplied two sessions chairs as well including our coordinator Marco Fraaje (below).